| Previous Episode | Next Episode | |:---: |:---: | | [[BDE280]] | [[BDE282]] | %%Post image thumbnail below.%%  > [!info|flex bg-c-gray] Episode Overview > > - **Date Aired:** [[01-18-2024]] > - **Title:** Disease X & Davos > - **Episode:** 281 > - **Description:** #Davos2024, Coronavirus congressional hearings, & a new discovery from DRASTIC. > - **Link:** <https://rumble.com/v47vgnl-big-dig-energy-281-disease-x-and-davos.html> %%<https://historydraft.com/happened/what-happened/1-January/world>%% ## Replay %% Get embed URL then highlight and hit ALT + I%% <iframe src="https://rumble.com/embed/v45a52l/?pub=6eeyh" allow="fullscreen" allowfullscreen="" style="height:100%;width:100%; aspect-ratio: 16 / 9; "></iframe> <br> ## Greetings & Announcements 1. I'll be on [Simpcast](https://www.youtube.com/@ChrissieMayr/streams) this Sunday evening, January 21st. 2. The GPU saga continues. It was supposed to be here yesterday, and due to the snowpocalypse it is delayed until (hopefully) tomorrow. It got to my local post office earlier this afternoon, so fingers crossed! My computer still sounds like a swarm of angry bees, so again if I have to cut the show short I'm sorry. Hanging on by a thread baybee!  ## Segments ### Snowpocalypse 2024 [Link](https://twitter.com/accuweather/status/1747354380033016143)  [Link](https://twitter.com/myARDOT/status/1746995552242266352)  [Link](https://twitter.com/accuweather/status/1748105169030594628)  [Link](https://twitter.com/accuweather/status/1747730031390990828)  ### January 6th Pipe Bomb Story [Tucker Segment](https://twitter.com/TuckerCarlson/status/1748117563228483869): **Timestamps:** 3:20: Darren gives an overview.  Darren Beattie [Thread](https://twitter.com/DarrenJBeattie/status/1748093132044980447):  Full Article: [Secret Service Foreknowledge or Criminal Negligence? Damning New Evidence Surfaces In FBI's January 6 "Pipe Bomb" Story - Revolver News](https://revolver.news/2024/01/secret-service-foreknowledge-or-criminal-negligence-damning-new-evidence-surfaces-fbi-january-6-pipe-bomb-story/) ### Disease X & Davos From yesterday ([[01-17-2024]]) at the [[World Economic Forum]]: <iframe src="https://www.weforum.org/event_player/a0P68000005lBPbEAM//sessions/a0W68000008UKrfEAG?locale=en&lang=English&theme=dark" width="100%" height="950" frameborder="0" scrolling="no"></iframe> #### Speakers - **Tedros Adhanom Ghebreyesus**: Director-General, World Health Organization (WHO) - **Shyam Bishen**: Head, Centre for Health and Healthcare; Member of the Executive Committee, World Economic Forum Geneva - **Roy Jakobs**: President and Chief Executive Officer, Royal Philips - **Preetha Reddy**: Executive Vice-Chairperson, Apollo Hospitals Enterprise Ltd - **Nisia Trindade Lima**: Minister of Health, Ministry of Health of Brazil - **Nancy Brown**: Chief Executive Officer, American Heart Association - **Michel Demaré**: Chair of the Board, AstraZeneca Plc **John's Hopkins Bloomberg School of Public Health — [Disease X Medical Countermeasure Program](https://centerforhealthsecurity.org/our-work/research-projects/disease-x-medical-countermeasure-program)** <div style="left: 0; width: 100%; height: 0; position: relative; padding-bottom: 60%;"><iframe src="https://docs.google.com/viewer?embedded=true&url=https://centerforhealthsecurity.org/sites/default/files/2023-01/210507-disease-x-infographic.pdf" style="top: 0; left: 0; width: 100%; height: 100%; position: absolute; border: 0;" allowfullscreen></iframe></div> --- **Other Important [Segments](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/programme):** - [Putting a Price on Nature > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/putting-a-price-on-nature-d5fa83e9ab/) - [A Conversation with Antony Blinken, United States Secretary of State > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/a-conversation-with-antony-blinken-us-secretary-of-state/) - [Middle East Conflict: What Is the Endgame? > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/middle-east-conflict-what-is-the-endgame/) - [Diversity in Practice > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/diversity-in-practice/) - [Where Is Freedom of Expression Going? > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/where-is-freedom-of-expression-going/) - [Are Banks Ready for the Future? > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/are-banks-ready-for-the-future/) - [Does Finance Benefit People? > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/does-finance-benefit-people/) - [Protecting the Vulnerable Online > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/protecting-the-vulnerable-online/) - More than half of internet users worldwide aged 13 and older face at least one potential online threat. Cyberbullying, online harassment, hate speech and misinformation pose significant challenges. - What are the key developments in trust and safety online and what measures should stakeholders embrace to foster a safer internet for all? - This session is directly linked to the ongoing [Global Coalition for Digital Safety Initiative](https://initiatives.weforum.org/global-coalition-for-digital-safety/home). - [Net Zero Industries > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/green-manufacturing/) - [Special address by Javier Milei, President of Argentina > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/special-address-by-javier-milei-president-of-argentina/) - [Thinking Big on Digital Inclusion > World Economic Forum Annual Meeting | World Economic Forum](https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/thinking-big-on-digital-inclusion/) ### DRASTIC, USRTK, & DEFUSE  [Drama Leading Up to Article Being Published](https://twitter.com/BillyBostickson/status/1747853618492100690)  #### [US scientists proposed making viruses with features of SARS-CoV-2 in Wuhan](https://usrtk.org/covid-19-origins/scientists-proposed-making-viruses-with-unique-features-of-sars-cov-2-in-wuhan/) > American scientists planned to work with the Wuhan Institute of Virology to engineer novel coronaviruses with the features of SARS-CoV-2 the year before the virus emerged from that city, according to documents obtained by U.S. Right to Know.  [PDF Link](https://usrtk.org/wp-content/uploads/2024/01/USGS-DEFUSE-2021-006245-Combined-Records_Redacted.pdf) > While rare in nature, these features were central to the esoteric research interests of the scientists working with the Wuhan lab, those documents show. > > Scientists divided over the so-called "lab leak" and natural origin hypotheses have for years pored over the arcane language of a U.S.-China research proposal called "DEFUSE" describing coronavirus engineering experiments. [PDF Link](https://drasticresearch.files.wordpress.com/2021/09/main-document-preempt-volume-1-no-ess-hr00118s0017-ecohealth-alliance.pdf) <div style="left: 0; width: 100%; height: 0; position: relative; padding-bottom: 60%;"><iframe src="https://docs.google.com/viewer?embedded=true&url=https://s3.documentcloud.org/documents/21066966/defuse-proposal.pdf" style="top: 0; left: 0; width: 100%; height: 100%; position: absolute; border: 0;" allowfullscreen></iframe></div> > The DEFUSE grant proposal was led by EcoHealth Alliance President Peter Daszak. > > Now, drafts and notes uncovered through the Freedom of Information Act reveal fresh details about the intended research.  > > Specifically, the scientists sought to insert furin cleavage sites at the S1/S2 junction of the spike protein; to assemble synthetic viruses in six segments; to identify coronaviruses up to 25 percent different from SARS; and to select for receptor binding domains adept at infecting human receptors. Side note: Synthetic viruses are viruses that have been created or modified in a laboratory setting. Scientists manipulate the genetic material to study their properties and understand how they work.  > The genome of SARS-CoV-2, the virus that causes COVID-19, matches the viruses described in the research proposal: > > - SARS-CoV-2 has a furin cleavage site positioned in the spike protein at the S1/S2 junction. The furin cleavage site supercharged the virus into the worst pandemic pathogen in a century. Virologists have yet to identify one in any other related coronavirus. > - SARS-CoV-2 can be divided into six contiguous genomic pieces by the restriction enzymes Bsal and BsmBI. These restriction enzymes occur in nature but can also be used in the lab to splice viruses. A trio of scientists estimated in a [2022 analysis](https://www.biorxiv.org/content/10.1101/2022.10.18.512756v1.full.pdf) that the likelihood of seeing the pattern found in SARS-CoV-2 in nature would be [remote](https://usrtk.org/covid-19-origins/preprint-covid-19-shows-fingerprint-of-laboratory-engineering/). Orders for one of these restriction enzymes, BsmBI, can be found in the documents. > <div style="left: 0; width: 100%; height: 0; position: relative; padding-bottom: 60%;"><iframe src="https://docs.google.com/viewer?embedded=true&url=https://www.biorxiv.org/content/10.1101/2022.10.18.512756v1.full.pdf" style="top: 0; left: 0; width: 100%; height: 100%; position: absolute; border: 0;" allowfullscreen></iframe></div> > - SARS-CoV-2 emerged highly infectious, without evolving much in humans. The virus “came out of the box ready to infect.” The receptor binding domain appeared “finely tuned” for the human ACE2 receptor yet had little genetic variation when first spilling over into humans, presenting a difficult “[paradox](https://usrtk.org/covid-19-origins/visual-timeline-proximal-origin/)” to virologists who sought to prove it emerged naturally. The documents confirm the scientists working with the Wuhan lab sought to select for receptor binding domains that bind well to human ACE2 in their research. > - The genome of SARS-CoV-2 falls within the range of a [25 percent](https://www.thelancet.com/action/showPdf?pii=S2666-5247%2821%2900174-9) genetic difference from SARS. > - <div style="left: 0; width: 100%; height: 0; position: relative; padding-bottom: 60%;"><iframe src="https://docs.google.com/viewer?embedded=true&url=https://www.thelancet.com/action/showPdf?pii=S2666-5247%2821%2900174-9" style="top: 0; left: 0; width: 100%; height: 100%; position: absolute; border: 0;" allowfullscreen></iframe></div> [Tweet Link](https://twitter.com/R_H_Ebright/status/1748148168393462157)  > The documents reveal for the first time that a virologist working with the Wuhan lab planned to engineer new spike proteins – in contrast with the collaboration's public work to insert whole spike proteins into viral backbones. Language in the proposal indicates this work may have involved unpublished viruses, generating unpublished engineered spike proteins. > > This American virologist, University of North Carolina Prof. Ralph Baric, was set to engineer twenty or more "chimeric" SARS-related viral spike proteins per year of the proposal, and two to five full-length engineered SARS-related viruses. Documents [previously reported by U.S. Right to Know](https://usrtk.org/covid-19-origins/american-scientists-misled-pentagon-on-wuhan-research/) show that some of the experimentation would secretly occur in Wuhan at a lower biosafety level than specified in the grant, apparently to save costs. > > The documents challenge an argument made by the National Institutes of Health and some virologists against the relevance of the research proposal to the origins of the pandemic. They have argued that this U.S.-China scientific collaboration only planned to engineer viruses starting with viral backbones already in the public literature, and that these viral backbones are too dissimilar to have played a role in the pandemic.  > > The new documents however reveal that the scientists planned to use new reverse genetics systems and test viruses *in vivo* — in other words, to engineer live novel viruses. > > The documents describe the SARS-related viruses to be studied in the grant as posing "a clear-and-present danger of a new SARS-like pandemic."  > > The documents do not prove a precise step-by-step instruction manual for how SARS-CoV-2 was generated in the lab. The genomes of some of the SARS-related viruses the scientists planned to work with remain unknown. But they do describe experiments that could have generated the virus' rare properties. They detail the scientists' interest in working with viruses precisely like SARS-CoV-2. [Continue Here](https://usrtk.org/covid-19-origins/scientists-proposed-making-viruses-with-unique-features-of-sars-cov-2-in-wuhan/#:~:text=SARS%2DCoV%2D2.-,The%20grant%20proposal%20was%20submitted,-to%20the%20Defense) --- [Thread Link](https://twitter.com/COVIDSelect/status/1748139966855598459)  %% FOOTER %% ---  --- ## Keep Digging %%Space%% ### Tags #Stream/BDE ### Footnotes & References